Each one gram of gel contains 0,25 mg of the active ingredient, tretinoin.
Retin-A® 0,025% Gel is indicated for topical application in the treatment of acne vulgaris. It contains tretinoin which is a form of vitamin A, and it belongs to a group of medications called topical retinoids.
Retinoids cause the outer layer of the skin to grow more rapidly and they increase skin-cell turnover. As a result, pores are less likely to become blocked, reducing the occurrence of whiteheads, blackheads and pimples. It’s often used for oily and acne-prone skin.
Retin-A® 0,025% Gel causes the skin to rapidly exfoliate; it also stimulates the production of collagen and elastin, resulting in brighter, plumper, and firmer skin.
DOSAGE AND DIRECTIONS FOR USE
Tretinoin has an inflammatory action which is reported to be related to its therapeutic activity. This inflammation appears to consist of an enlargement of vessels in the papillary body and a slight perivascular cellular infiltration. The inflammatory action may result from labialisation of lysosomes and the release of hydralases and proteases which are capable of inciting inflammatory reactions. It has been suggested that the therapeutic activity of tretinoin in the treatment of acne results from it increasing the rate of production of loose horny material. This increased production and resulting flow of dehiscing material to the surface prevents the impaction of horny material into comedones.